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Showing 1 - 20 of
20 matches in All Departments
K.W. Bock: The Aryl Hydrocarbon or Dioxin Receptor: Biologic and
Toxic Responses.- K. Grieshaber, I. Hardewig, U. Kreutzer, and
H.-O. Poertner: Physiological and Metabolic Responses to Hypoxia in
Invertebrates.- K.-W. Koch: Calcium as Modulator of
Phototransduction in Vertebrate Photoreceptor Cells.
P.J. Pearson, P.M. Vanhoutte: Vasodilator and Vasoconstrictor
Substances Produced by the Endothelium. L. Dux: Muscle Relaxation
and Sarcoplasmic Reticulum Function in Different Muscle Types. C.C.
Ashley, P.J. Griffith, T.J. Lea, I.P. Mulligan, R.e. Palmer, and
S.J. Simnett: Barnacle Muscle: Ca2+ Activation and Mechanics.
This special volume provides up-to-date information on research
dealing with the regulation of the biosynthesis and degradation of
cyclic GMP and with the regulation of physiological systems by
cyclic GMP. The publication of this volume could not have come at a
more appropriate time, with significant work in this area having
led to our current understanding of the role of nitric oxide in
signal transduction, and the 1998 Nobel Prize in Medicine and
Physiology for Furchgott, Murad and Ignarro. Moreover, the
introduction in early 1998 of sildenafil (Viagra), a selective
inhibitor of a cyclic GMP phosphodiesterase, for the treatment of
erectile dysfunction in men represents the first successful
therapeutic application of an agent designed to alter the activity
of a molecular target in a cyclic GMP pathway.
J.A. Roth: Membrane-Bound Catechol-O-Methyltreansferase: A
Reevaluation of Its Role in the O-Methylation of the Catecholamine
Transmitters. D.J. Benos, S. Cunningham, R.R. Baker, K.B. Beason,
Y. Oh, and P.R. Smith: Molecular Characteristics of
Amiloride-Sensitive Sodium Channels. D. Pette and G. Vrbov :
Adaptation of Mammalian Skeletal Muscle Fibers to Chronic
Electrical Stimulation.
In this regular issue of Reviews of Physiology the first
contribution by Warth and Bleich is on K+ Channels and Colonic
Function, the second by Offermanns on Mammalian G-Protein Function
in vivo: New Insights Through Altered Expression, and the third
contribution by Tenenholz et al. (including one editor of the
series) on Structural Determinants of Scorpion Toxin Affinity: The
Charybdotoxin (alpha-KTX) Family of K+-channel Blocking Peptides.
R. Levenson: Isoforms of the Na,K-ATPase: Family Members in Search
of Function.- E. Petzinger: Transport of Organic Anions in the
Liver. An Update on Bile Acid, Fatty Acid, Monocarboxylate, Anionic
Amino Acid, Cholephilic Organic Anion and Anionic Drug Transport.-
E. Schultz, K.M. McCormick: Skeletal Muscle Satellite Cells.
Contents: R.L. Moss, G.M. Diffee, M.L. Greaser: Contractile
Properties of Skeletal Muscle Fibers in Relation to Myofibrillar
Protein Isoforms.- J.E. Wilson: Hexokinases.- J. Rassow, N.
Pfanner: Molecular Chaperones and Intracellular Protein
Translocation.- H. Fuder, E. Muscholl: Heteroreceptor-Mediated
Modulation of Noradrenaline and Acetylcholine Release from
Peripheral Nerves.
Cook et al.: Phospholipases C and D in Mitogenic Signal
Transduction. Moolenaar et al: Lysophosphatidatic Acid: A Bioactive
Phospholipid with Growth Factor-Like Properties. Kozma et al.:
Serine/Threonine Kinases in thePropagation of the Early Mitogenic
Response. Diringer et al: A Retrospective on Transformation, Growth
Control, and some Peculiarities of Lipid Metabolism. Villereal et
al.: Calcium Signals in Growth Factor Signal Transduction.
Wakabayashi et al.: Structure Function of the Growth
Factor-Activatable Na+/H+ Exchanger. Herrlich et al.: DNA
Damage-Induces Gene Expression: Signal Transduction and Relation to
Growth Factor Signaling. Lucibello et al.: Transcription Factor
Encoding Oncogenes
In the series Reviews of Physiology, Biochemistry and Pharmacology
three excellent contributions by Ruth Heidelberger (Houston, TX,
USA) with Electrophysiological Approaches to the Study of Neuronal
Exocytosis and Synaptic Vesicle Dynamics and Kay Truscott et al.
(Freiburg, Germany) with Transport of Proteins Into Mitochondria
and Randall K. Powers and Marc D. Binder (Seattle, WA, USA) with
Input-Output Functions of Mammalian Motoneurons form another
outstanding volume.
In this second special issue on signal transduction leading
specialists in their fields again present overviews of topics
related to the highly topicalsubject of signal transduction. The
first contribution, by Keppler, deals with the biosynthesis,
transport, inactivation, and analysis of leukotrienes. Mohr et al.
present an excellent overview of the biology of the peptide hormone
oxytocin and its role in signal transduction.The review by Holzer
describes the significance of peptinergic sensory neurons in the
control of vascular functions. In the contribution by Wolf etal the
molecular biology of the Y chromosome is discussed.
W. Ulbricht: Effects of veratridine on sodium currents and fluxes.
W. Meyerhof: The elucidation of somatostatin receptor functions: a
current view.M. Leist, F. Gantner, g. Kunstle and A. Wendel:
Cytokine-mediated hepatic apoptosis.
In this volume of Reviews of Physiology, Biochemistry and
Pharmacology there a contributions by M.D. Swope, E. Lolis,
F.Hofmann, L. Lacinova, N. Klugbauer, M. Hermann, P. Berger, S.S.
Shen, J.S. Kim, M.E. Weksler, M. Hirsch-Kauffmann and M. Schweiger.
H. Wegele, L. M ller, and J. Buchner: Hsp70 and Hsp90 A Relay
Team for Protein Folding
R. Sch lein: The Early Stages of the Intracellular Transport of
Membrane Proteins: Clinical and Pharmacological Implications
L. Schild: The Epithelial Sodium Channel: From Molecule to
Disease
In this volume of Reviews of Physiology, Biochemistry and
Pharmacology there a contributions by M.D. Swope, E. Lolis,
F.Hofmann, L. Lacinova, N. Klugbauer, M. Hermann, P. Berger, S.S.
Shen, J.S. Kim, M.E. Weksler, M. Hirsch-Kauffmann and M.Schweiger.
Due to escalating pressures from domestic and global competitors,
and changes in so- cietal norms, laws, and the economy during the
past decade, it has become clear to many executives that people are
increasingly important to the success and survival of their
companies, but also increasingly more complex to manage. Moreover,
it is likely that the complexity will increase even further in the
Nineties as global and regional econ- omies continue to emerge. In
Europe, entirely new political entities will contribute to
complexity and pose difficult problems in a multi-ethnic society.
While creating many challenges, these pressures are also creating
excellent opportunities for human resource (HR) executives to make
substantial contributions to their organiza- tions. Whether such
opportunities are realized, however, will depend upon how well
these executives develop, refme, and leverage both their business
and human resource management skills. This book, which is a
collaborative effort on the part of the editors of the Human Re-
source Planning journal and Gabler Publishing, is intended for both
line and HR ex- ecutives interested in more effectively managing
their employees. It is a compilation of selected cutting-edge
articles published in the journal during the past five years. It is
di- vided into the following seven sections which represent
important HR issues facing ex- ecutives today (and in the near
future): Section 1. The Human Resource Function in Transition
Section 2. Strategic Human Resource Planning Section 3. Mergers and
AcquiSitions Section 4. Performance Appraisal and Performance
Management Section 5.
FunktioneHe Untersuchungen des Stuhlkontinenzorgans gewinnen in der
Proktologie und Dickdarmchirurgie zunehmend an praktischer
Bedeutung. Die Elektromyographie und die Manometrie nehmen in
dieser Funk- tionsdiagnostik eine zentrale SteHung ein. Haufig
bieten sie die einzi- ge Moglichkeit einer Differentialdiagnostik
der Stuhlkontinenz. Dar- iiberhinaus steHen sie eine wichtige
Entscheidungshilfe nachchirur- gischen Eingriffen am Kontinenzorgan
dar. Kann zum Beispiel ein entlastender Anus praeter naturalis
zuriickverlegt werden, ohne daB mit einer StOrung der natiirlichen
analen Kontinenz zu rechnen ist? Die Funktionsdiagnostik des
Stuhlkontinenzorgans mit Hilfe der Manometrie und Elektromyographie
befindet sich noch in Entwick- lung. Verbindliche Richtlinien sind
noch nicht erarbeitet. Herr Schweiger hat sich diesem Problem
besonders gewidmet und objektive Kriterien der Stuhlkontinenz,
sowie der quantitativen Un- terscheidung der glatten und
quergestreiften Analsphinktermuskula- tur erarbeitet. Das
vorliegende Buch bildet einen wertvoHen Beitrag fUr die
Funktionsdiagnostik des Stuhlkontinenzorgans. Erlangen, Juni 1982
F. P. Gall VII Inhaltsverzeichnis 1 Einleitung . . . . . . . . . .
. . . . . . . . .. . . 1 . . . . 2 Anatomische Vorbemerkungen . . .
. . . . . . . .. . . 3 . 3 Methodik der Analsphinkterkennlinie ....
. . . . .. . 6 3.1 Untersuchungsmethode.................. 6 3.1.1
MeBeinheit . . . . . . . . . . . . . . . . . .. . . . 6 . . . 3.1.2
Untersuchungsvorgang .................. 8 3.2 Aufstellungder
Analsphinkterkennlinie ... . . . .. . 10 3.2.1
TheoretischeHerleitung . . . . . . . . . . . . .. . . 10 . . 3.2.2
Praktisches Beispiel .................... 13 3.2.3 Auswertungder
Analsphinkterkennlinie . . . . . . .. . 14 4
Patientengut........................ 15 4.1 Klinische Kriterien der
Stuhlinkontinenz . . . . . . . 15 4.2 Voruntersuchungsreihe
.................. 15 4.3
UntersuchungsreihefiirdieAnalsphinkterkennlinie... 16 4.3.1
Normalgruppe . . . . . . . . . . . . . . . . .. . . 16 . . .
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